Ungcoliseko lomoya wangaphandle kunye ne-particulate matter (PM) zihlelwa njengeQela loku-1 le-carcinogens yabantu kumhlaza wemiphunga. Unxulumano olungcolisekileyo kunye nomhlaza we-haematologic luyacebisa, kodwa ezi zomhlaza zine-aetiologically heterogeneous kunye nohlobo lovavanyo olusezantsi alukho.
Iindlela
I-American Cancer Society Society Cancer Prevention Study-II Cohort yeSondlo yasetyenziselwa ukuhlola unxulumano longcoliseko lomoya lwangaphandle kunye nomhlaza wehamatologic yabantu abadala. Uqikelelo lwenqanaba leqela lebhloko yobalo lonyaka lwe-particle (PM2.5, PM10, PM10-2.5), i-nitrogen dioxide (NO2), i-ozone (O3), i-sulphur dioxide (SO2), kunye ne-carbon monoxide (CO) yabelwe iidilesi zokuhlala. Umlinganiselo weengozi (HR) kunye ne-95% yamathuba okuzithemba (CI) phakathi kwezinto ezingcolisa ixesha kunye nee-haematologic subtypes ziqikelelwe.
Iziphumo
Kubathathi-nxaxheba abayi-108,002, ngama-2659 eziganeko zomhlaza zehamatologic zachongwa ukususela ngo-1992–2017. Uxinzelelo oluphezulu lwe-PM10-2.5 ludibene ne-mantle cell lymphoma (HR nge-4.1 μg / m3 = 1.43, 95% CI 1.08-1.90). I-NO2 idibaniswe ne-Hodgkin lymphoma (HR nge-7.2 ppb = 1.39; 95% CI 1.01-1.92) kunye ne-marginal zone lymphoma (HR nge-7.2 ppb = 1.30; 95% CI 1.01-1.67). I-CO idibaniswe nommandla we-marginal (HR nge-0.21 ppm = 1.30; 95% CI 1.04-1.62) kunye ne-T-cell (HR nge-0.21 ppm = 1.27; 95% CI 1.00-1.61) i-lymphomas.
Izigqibo
Indima yongcoliseko lomoya kumhlaza we-haematologic isenokuba ibingacingelwanga ngaphambili ngenxa yohlobo oluncinane lwe-heterogeneity.
Sifuna umoya ococekileyo ukuze siphefumle, kwaye uninzi lwezicelo lufuna iimpawu zomoya ezifanelekileyo ukuze zisebenze ngokufanelekileyo, ngoko ke kubalulekile ukuqaphela indawo esingqongileyo. Kule nkalo, sinikezela ngoluhlu lwezinzwa zokusingqongileyo zokubona izinto ezifana ne-ozone, i-carbon dioxide kunye ne-volatile organic compounds (VOCs).
Ixesha lokuposa: May-29-2024